Indications
Increased tone of skeletal muscles due to organic neurological disorders (e.g. injury of the pyramidal tract, multiple sclerosis, myelopathy, encephalomyelitis etc.), muscular hypertension, muscular spasm, muscular contracture, rigidity, spinal automatism and discopathy, obliterative vascular diseases (obliterative arteriosclerosis, diabetic angiopathy, obliterative thromboangitis, Raynaud's disease, diffuse scleroderma) and disorders due to injured innervation of the vessels (acrocyanosis, intermittent angioneurotic dysbasia). In individual cases, post-thrombotic venous and lymphatic circulation disorders, crural ulcer.
Pharmacology
Tolperisone Hydrochloride is a centrally acting muscle relaxant. It effectively reduces muscular hypertonicity, improves peripheral blood flow by vasodilatation and reduces pain. Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthetic action.
Dosage & Administration
The usual dose is one ampoule twice daily by intramuscularly. Injection should be given slowly. Accordingly to age and symptom, the dosage may be changed.
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Contraindications
Hypersensitivity to any component of the product, Myasthenia gravis, Nursing mother
Side Effects
Sometimes, muscular weakness, headache, nausea, vomiting and rarely hypersensitivity reactions may occur as side effects.
Pregnancy & Lactation
Tolperisone hydrochloride should be used in pregnancy according to physician's advice. Tolperisone hydrochloride should not be used during breast feeding.
Precautions & Warnings
In case of children, the prescribed dose and duration of treatment should closely be observed.
Overdose Effects
In the event of over dosage, supportive therapy may be substituted.
Therapeutic Class
Centrally acting Skeletal Muscle Relaxants, Locally acting Skeletal Muscle Relaxants
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.