Pronacillin IM Injection

All beta lactum antibiotics bind to bacterial cell receptors. These receptors are involved in the cross-linking of peptide side chain-transpeptidation reaction. Gram-positive bacteria have more receptors for beta lactums than gram-negative organisms. After beta lactums have attached to the cell receptors, peptidoglycan synthesis (cell wall) is inhibited because the activity of transpeptidation enzyme is blocked leads to the formation of defective cell wall that are osmotically unstable. Cell death result from cell lysis.

By deep intramuscular injection only. This 40 injection should be diluted with 10ml Water for Injection and Injected at 24 hours intervals. The drug should be used for 1-2 more days after relief of symptoms.

Cow, Buffalo, Horse, Sheep & Goat-

• 10 kg body weight: 0.2-0.5 ml daily dose
• 50 kg body weight: 1-2.5 ml daily dose
• 100 kg body weight: 2-5 ml daily dose
• 200 kg body weight: 4-10 ml daily dose

Cat, Dog & other small animals-

• 10 kg body weight: 0.5-1 ml daily dose
• 20 kg body weight: 1-2 ml daily dose

This injection is contraindicated in animals hypersensitive to active ingredients.

Swelling and redness at the site of injection may occur. Contact dermatitis may also result.

This injection is safe for use in pregnant and in lactating animals. However, in case of lactating animals higher dosage rate have the disadvantage of increasing penicillin residues in milk.

To minimize local irritation at the site of injection, the area should be rubbed gently. As penicillin hypersensitivity may give rise to skin rash and anaphylaxis, it is advisable to perform a test before administering this injection. An antihistaminic injection may be administered to avoid such a reaction.

Store in a cool & dry place. Protect from sunlight & moisture. Keep out of reach of children.