Generic list of "Cytotoxic Chemotherapy"

Abiraterone Acetate

Abiraterone Acetate is a CYP17 inhibitor indicated in combination with prednisone for the treatment of patients with Metastatic castration-resistant prostate cancer (CRPC). Metastatic high-risk castration-sensitive ...

Aflibercept, in combination with 5-fluorouracil, leucovorin, irinotecan-(FOLFIRI), is indicated for patients with metastatic colorectal cancer (mCRC) that is resistant to or has progressed following an ...

Apalutamide is an androgen receptor inhibitor indicated for the treatment of patients with- metastatic castration-sensitive prostate cancer non-metastatic castration-resistant prostate cancer.

Chronic Lymphocytic Leukemia (CLL): Bendamustine is indicated for the treatment of patients with chronic lymphocytic leukemia. Efficacy relative to first line therapies other than chlorambucil has not ...

Bleomycin Sulfate

Bleomycin sulfate should be considered a palliative treatment. It has been shown to be useful in the management of the following neoplasms either as a single agent or in proven combinations with other ...

Brigatinib is indicated for the treatment of patients with anaplastic lymphoma kinase (ALK)-positive metastatic Non-small cell lung cancer (NSCLC) who have progressed on or are intolerant to Crizotinib.

Busulfan is indicated for Chronic myeloid leukemia, Polycythemia vera, Essential thrombocythemia, Conditioning regimens for bone marrow transplantation, Conditioning regimens for bone marrow transplantation.

In combination with prednisone or prednisolone, for patients with hormone refractory metastatic prostate cancer previously treated with a docetaxel-containing regimen. Due to high incidence of neutropenia ...

Capecitabine is a nucleoside metabolic inhibitor with antineoplastic activity indicated for: Adjuvant Colon Cancer: Patients with Dukes'C colon cancer. Metastatic Colorectal Cancer: First-line as ...

Carboplatin Injection is indicated for the initial treatment of advanced ovarian carcinoma of epithelial origin in established combination with other approved chemotherapeutic agents. It is also indicated ...

Carmustine injection is indicated as palliative therapy as a single agent or in established combination therapy in the following: Brain tumors glioblastoma, brainstem glioma, medulloblastoma, astrocytoma ...

Hodgkin's disease, certain forms of non-Hodgkin's lymphoma, chronic lymphocytic leukemia, Waldenstrom's macroglobulinaemia.

Metastatic Testicular Tumors: In established combination therapy with other approved chemotherapeutic agents in patients with metastatic testicular tumors who have already received appropriate surgical ...

Cyclophosphamide

Cyclophosphamide, although effective alone in susceptible malignancies, is more frequently used concurrently or sequentially with other antineoplastic drugs. The following malignancies are often susceptible ...

Cytarabine may be used alone or in combination with other chemotherapeutic agents. It is indicated for induction of remission of leukaemia, particularly for acute myeloid leukaemia, in adults and children ...

Dacarbazine is indicated in the treatment of metastatic malignant melanoma. In addition, Dacarbazine is also indicated for Hodgkin's disease as a second-line therapy when used in combination with other effective agents.

Dacomitinib is indicated for the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 19 deletion or exon 21 L858R substitution ...

Darolutamide is indicated for the treatment of patients with non-metastatic castration resistant prostate cancer.

Daunorubicin in combination with other approved anticancer drugs is indicated for remission induction in acute nonlymphocytic leukemia (myelogenous, monocytic, erythroid) of adults and for remission induction ...

Docetaxel Trihydrate

Docetaxel is a microtubule inhibitor indicated for: Breast Cancer (BC): single agent for locally advanced or metastatic BC after chemotherapy failure; and with doxorubicin and cyclophosphamide as ...

Doxorubicin Hydrochloride

Doxorubicin Hydrochloride is indicated: As a component of multiagent adjuvant chemotherapy for treatment of women with axillary lymph node involvement following resection of primary breast cancer ...

Enzalutamide is indicated for the treatment of patients with: castration-resistant prostate cancer (CRPC) metastatic castration-sensitive prostate cancer (mCSPC)

Epirubicin Hydrochloride

Epirubicin Injection is indicated as a component of adjuvant therapy in patients with evidence of axillary node tumor involvement following resection of primary breast cancer.

Etoposide is indicated in the management of small cell lung cancer: Etoposide is indicated in combination with other approved chemotherapeutic agents as first-line treatment in patients with small cell lung cancer.

Fludarabine Phosphate

Fludarabine Phosphate is indicated for the treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to or whose disease has progressed during treatment with at ...

Fulvestrant is an estrogen receptor antagonist indicated for the treatment of: Hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer in postmenopausal ...

Non-Small Cell Lung Cancer: Gemcitabine, in combination with Cisplatin, is indicated as a first-line treatment of patients with locally advanced (inoperable Stage lllA or IIIB) or metastatic (Stage IV) ...

Significant tumour response to Hydroxyurea has been demonstrated in melanoma, resistant chronic myeloid leukaemia and recurrent metastatic or inoperable carcinoma of the ovary. Hydroxyurea used concomitantly ...

Idarubicin Hydrochloride

Idarubicin hydrochloride in combination with other approved antileukemic drugs is indicated for the treatment of acute myeloid leukemia (AML) in adults. This includes French-American- British (FAB) classifications M1 through M7.

Ifosfamide Injection is indicated for use in combination with certain other approved antineoplastic agents for third-line chemotherapy of germ cell testicular cancer. It should be used in combination ...

Irinotecan Hydrochloride

Irinotecan Injection is indicated as a component of first-line therapy in combination with 5- Fluorouracil (5-FU) and Leucovorin (LV) for patients with metastatic carcinoma of the colon or rectum. Irinotecan ...

L-Asparginase injection is indicated as a component of a multi-agent chemotherapeutic regimen for the treatment of patients with acute lymphoblastic leukemia (ALL).

Lapatinib is indicated in combination with: Capecitabine for the treatment of patients with advanced or metastatic breast cancer whose tumors overexpress human epidermal growth factor receptor 2 (HER2) ...

Larotrectinib is indicated for the treatment of adult and pediatric patients with solid tumors that: have a neurotrophic receptor tyrosine kinase (NTRK) gene fusion without a known acquired resistance ...

Multiple Myeloma: Lenalidomide in combination with Dexamethasone is indicated for the treatment of adult patients with multiple myeloma (MM). Lenalidomide is indicated as maintenance therapy in adult ...

Lenvatinib Mesylate

Lenvatinib is a kinase inhibitor that is indicated: Differentiated Thyroid Cancer: Lenvatinib is indicated for the treatment of patients with locally recurrent or metastatic, progressive, radioactive ...

Lorlatinib as monotherapy is indicated for the treatment of adult patients with anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer (NSCLC) whose disease has progressed after ...

Multiple Myeloma-Conditioning Treatment: Melphalan is indicated for use as a high-dose conditioning treatment prior to hematopoietic progenitor (stem) cell transplantation in patients with multiple myeloma.

Mercaptopurine is indicated for maintenance therapy of acute lymphatic (lymphocytic, lymphoblastic) leukemiaas part of a combination regimen. The response to this agent depends upon the particular subclassification ...

Nab-Paclitaxel [Nanoparticle Albumin-Bound Paclitaxel]

Metastatic Breast Cancer: Nab-Paclitaxel is indicated for the treatment of breast cancer after failure of combination chemotherapy for metastatic disease or relapse within 6 months of adjuvant chemotherapy ...

Niraparib is indicated for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in a complete or partial response to platinum-based chemotherapy.

Osimertinib is indicated for the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors have epidermal growth factor receptor (EGFR) exon 19 deletions or exon ...

Oxaliplatin, used in combination with infusional 5-fluorouracil/folinic acid, is indicated for: Adjuvant treatment of stage III colon cancer in patients who have undergone complete resection of the ...

Pemetrexed is indicated in Non-Squamous Non-Small Cell Lung Cancer (NSCLC): in combination with Pembrolizumab and platinum chemotherapy, for the initial treatment of patients with metastatic non-squamous ...

Ramucirumab is a human vascular endothelial growth factor receptor 2 (VEGFR2) antagonist indicated: As a single agent or in combination with paclitaxel, for treatment of advanced or metastatic gastric ...

Newly Diagnosed Glioblastoma Multiforme: Temozolomide is indicated for the treatment of adult patients with newly diagnosed glioblastoma multiforme concomitantly with radiotherapy and then as maintenance ...

Ovarian Cancer: Topotecan for injection, as a single agent, is indicated for the treatment of patients with metastatic carcinoma of the ovary after disease progression on or after initial or subsequent ...

Treosulfan is indicated in combination with fludarabine as part of conditioning treatment prior to allogeneic hematopoietic stem cell transplantation (alloHSCT). in adult patients with AML or MDS ...

Tucatinib is indicated in combination with trastuzumab and capecitabine for treatment of adult patients with advanced unresectable or metastatic HER2-positive breast cancer, including patients with brain ...

Venetoclax in combination with Rituximab is indicated for the treatment of adult patients with chronic lymphocytic leukemia (CLL) who have received at least one prior therapy. Venetoclax monotherapy ...

Vinblastine Sulfate

Vinblastine is effective as a single agent, but its therapeutic effect is enhanced when used in combination with other antineoplastic drugs. Vinblastine has been used in the treatment of Hodgkin’s ...

Vincristine Sulfate

Vincristine sulfate is indicated in acute leukemia. Vincristine sulfate has also been shown to be useful in combination with other oncolytic agents in Hodgkin's disease, non-Hodgkin's malignant lymphomas ...

Vinorelbine Tartrate

Vinorelbine is indicated: In combination with cisplatin for first-line treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) As a single agent, for the treatment ...