Gentamicin Sulfate (Topical)

Indications

Indicated for Burn, Eczema, Seborrhetic dermatitis, Ecthyma, Excoriation, Folliculitis, Furunculosis, Insect bites and stings, Lacerations and abrasions, Paronychia, Pyoderma gangrenosum, Skin cysts and abscesses, Stasis ulcers and infected skin ulcers, Bacterial, fungal or viral superinfection, Sycosis barbae, minor surgical wounds, infected contact dermatitis caused by susceptible organisms.

Pharmacology

Gentamicin Sulphate is an aminoglycoside antibiotic. It is a proven bactericidal antibiotic active against Gram-positive & Gram-negative pathogens including E. coli, Klebsiella, Proteus, Pseudomonas aeruginosa and penicillin resistant strains of Staph. aureus. In common with other aminoglycoside antibiotics, it appears to interfere with protein synthesis of the bacterial cell.

Dosage & Administration

Apply 3 times daily. Before application, the area should be washed with soap and water and dried thoroughly. If crusts present, it should be removed before the application of ointment to provide maximum contact with the infecting organisms.
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Contraindications

Gentamicin injection and Gentamicin ointment are contraindicated to patients hypersensitive to Gentamicin. It is contraindicated in pregnancy and myasthenia gravis.

Side Effects

Itching, redness, swelling or other signs of irritation.

Pregnancy & Lactation

Pregnancy Category D. Small amounts of Gentamicin have been detected in breast milk. So, it is recommended that breastfeeding should be discontinued during treatment.

Precautions & Warnings

Gentamicin Ointment should not be applied to patients hypersensitive to Gentamicin.

Therapeutic Class

Topical Antibiotic preparations

Storage Conditions

Store below 30°C and protected from light.