Carica Papaya Leaf Extract
Indications
Carica Papaya Leaf Extract is indicated for -
- Thrombocytopenia (low platelet count) associated with Dengue.
- Thrombocytopenia (low platelet count) induced by chemotherapy.
- Increases the taste of food
- Aids in digestion
- Eliminates constipation
- Reduces inflammation of the stomach and colon
- Keeps the liver clean
- Boost immunity
- Removes acne
- Ensures healthy and beautiful skin
- Relieves menstrual pain.
Pharmacology
Carica papaya, belongs to the plant family Caricaceae, is an economically important fruit crop worldwide. Many scientific works have been carried out to evaluate the benefit of different parts of papaya plant including fruits, seeds, leaves, rind, shoots, roots or latex. The leaf is considered non-toxic as its lethal dose is >15 g/kg body weight.
Preclinical studies in mice demonstrated encouraging the activity of Carica papaya powder in increasing platelet count. Recently in vitro study showed that Carica papaya leaves extract exhibited significant inhibition of hemolysis probably due to its membrane stabilizing potency.
Preclinical studies in mice demonstrated encouraging the activity of Carica papaya powder in increasing platelet count. Recently in vitro study showed that Carica papaya leaves extract exhibited significant inhibition of hemolysis probably due to its membrane stabilizing potency.
Dosage & Administration
Adults: The recommended dose of 250 mg 1-2 capsules daily 2-3 times a day for 5-12 days.
For children more than 1 year and less than 5 years: 1 teaspoonful (5ml) three times a day for 5 days
For children more than 5 years and less than 18 years: 2 teaspoonful (10ml) three times a day for 5 days
Above 18 years & above: 3 teaspoonful (15 ml) three times a day for 5 days or as directed by a physician
For children more than 1 year and less than 5 years: 1 teaspoonful (5ml) three times a day for 5 days
For children more than 5 years and less than 18 years: 2 teaspoonful (10ml) three times a day for 5 days
Above 18 years & above: 3 teaspoonful (15 ml) three times a day for 5 days or as directed by a physician
* চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Interaction
It has been found to increase the bioavailability of amiodarone and therefore the dose should be adjusted accordingly when co-administered with Carica papaya leaf extract. In vitro study demonstrated potentiating the action of various antibiotics like penicillin G, ampicillin, amoxyclav, cephalothin, polymyxin B, rifampicin, amikacin, nalidixic acid, gentamycin, chloramphenicol, ofloxacin when co-administered with C. papaya. The extract of C. papaya with antimicrobial agents possesses synergistic properties which act against pathogenic organisms.
Contraindications
Hypersensitivity, Pregnancy. In males with prostate dysfunction, such as BPH or prostate cancer, Carica
papaya should be avoided as it increases the iron absorption. Excess iron may increase oxidative stress, especially in the aging male. Iron overload may increase the risk of developing prostate cancer.
papaya should be avoided as it increases the iron absorption. Excess iron may increase oxidative stress, especially in the aging male. Iron overload may increase the risk of developing prostate cancer.
Side Effects
No health hazards or side effects are known in conjunction with the proper administration of designated therapeutic dosages.
Pregnancy & Lactation
Not recommended in pregnancy and lactation.
Precautions & Warnings
Should be used with caution in individuals with bleeding disorders or those taking blood thinning medications such as aspirin or warfarin. Co-administration of extracts of Carica papaya with oral hypoglycemic may lead to very low blood glucose as observed in one of the experimental animal study. Thus it is important to closely monitor the blood glucose levels regularly to avoid hypoglycemia.
Therapeutic Class
Herbal and Nutraceuticals
Storage Conditions
Keep away from direct sunlight & moisture. Keep below 30°C temperature in cool & dry place. Keep the medicine out of reach of children.
