Ampicillin Sodium
Veterinary
Indications
Indicated in different bacterial diseases of animals e.g. Pneumonia, Footrot, Enteritis, Salmonellosis, Calf scour, Infected wound, Fever, Colibaciliosis, Metritis, Mastitis, Pyelonephritis, Black quarter, Joint infection, Kidney infection, Haemorrhagic septicemia etc.
Highlighting Points:
Highlighting Points:
- True broad spectrum antibiotic.
- Low resistance in veterinary use.
- Well absorbed following IM or IV administration.
- Rapidly and widely distributed into most body fluid.
- Ensures quicker action.
- Safe in pregnancy and lactating period.
- Reduces the chance of diarrhea by parenteral administration
- The half life is approximately 60-90 minutes.
- Tissue drug concentrations may be higher than serum concentrations.
Pharmacology
By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, Ampicillin inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that Ampicillin interferes with an autolysin inhibitor.
Dosage & Administration
Ampicillin Sodium powder for injection should be mixed with 10 ml WFI and then administer by IM or IV route. The parenteral dose is 7 mg/kg.
Cattle, Buffalo:
Cattle, Buffalo:
- 50 Kg: 1.0 to 2.5 ml Once-daily but in severe infection twice daily.
- 100 Kg: 2.0 to 5.0 ml Once-daily but in severe infection twice daily.
- 200 Kg: 4.0 to 10.0 ml Once-daily but in severe infection twice daily.
- 10 Kg: 0.2 to 0.5 ml Once-daily but in severe infection twice daily.
- 20 Kg: 0.4 to 1.0 ml Once-daily but in severe infection twice daily.
- 10 Kg: 0.5 to 1.0 ml Once-daily but in severe infection twice daily.
- 20 Kg: 1.0 to 2.0 ml Once-daily but in severe infection twice daily.
* চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Contraindications
The drug is contraindicated in animals hypersensitive to Ampicillin.
Side Effects
In recommended dosage, Ampicillin Sodium is relatively non-toxic and free from adverse effect. Moreover, skin rash, pain at the site of injection, diarrhea etc. may occur.
Pregnancy & Lactation
Ampicillin Sodium is safe in pregnancy state and in lactating period in animals.
Precautions & Warnings
For veterinary use only. To be dispensed only by or on the prescription of a registered veterinary doctor. Store in a cool, dry place. Protect from light and keep out of reach of children.
Storage Conditions
Store in a cool & dry place. Protect from sunlight & moisture. Keep out of reach of children.
