Amprolium + Ethopabate + Sulphaquinoxaline + Vitamin K3 + Vitamin C

Veterinary

Indications

This is an anticoccidial drug for treatment and control of coccidiosis in poultry. This combination is developed to take the advantage of the synergistic benefits of the three chemicals against a mixed infection of Eimeria acervulina, Eimeria maxima, Eimeria necatrix, Eimeria tenella, Eimeria brunette at relatively safe levels of each drug by itself.

Benefits:
  • Controls coccidiosis of poultry without hampering production.
  • Effective to treat mixed coccidial infection.
  • Besides coccidia pathogens, acts on many gm(+)ve & gm(-)ve bacteria; so cures the intestinal ulcer quickly.
  • Effective to coccidia pathogens which are resistant to sulfa drugs.
  • There is no side effect if use in recommended dosage.

Composition

Each gram soluble powder contains:
  • Amprolium 100 mg
  • Ethopabate 5 mg
  • Sulphaquinoxaline 60 mg
  • Vitamin K3 2 mg
  • Vitamin C 20 mg

Pharmacology

  • Amprolium is a competitive antagonist of Thiamine. It causes deficiency of Thiamine in protozoan body & stops protozoan metabolism.
  • Sulphaquinoxalin is a competitive antagonist of PABA which stops metabolism of protozoa and other gram-positive & gram-negetive bacteria. Amprolium & Sulphaquinoxalin acts synergistically.
  • Ethopabate increases the spectrum of activity into two fold and overcomes resistance which may be developed by the combination of Amprolium & Sulphaquinoxalin.
  • Vitamin K3 prevents hemorrhage.
  • Vitamin C acts as an anti-stress factor and synthesizes Collagen to repair intestinal ulcer.

Dosage & Administration

Treatment: 1 gm/2 litre of drinking water for 5-7 days.
Prevention: 1 gm/4 litre of drinking water for 3-4 days.
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Interaction

It is better not to use with Furazolidone. Amprolium and Furazolidone both are antagonized the utilization of thiamin. In this regards using both simultaneously may deficit thiamin in the system.

Precautions & Warnings

Drug Withdrawal: Use prohibited at least seven days before slaughter.

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

Available Brand Names