Sulphanilamide

Sulphanilamide Powder is used to treat sulphanilamide-sensitive organisms, notably streptococcal septicaemia; equine pneumonia, strangles, joint-ill, metritis in mares, cows and ewes. Sulphanilamide Powder is also used as a dusting powder for wounds by topical application.

Sulfanilamide is a competitive inhibitor of the bacterial enzyme dihydropteroate synthetase. This enzyme normally uses Para Amino Benzoic Acid (PABA) for synthesizing the necessary folic acid. The inhibited reaction is normally necessary in these organisms for the synthesis of folic acid. Thus Sulfanilamide inhibits microorganism replication.

Animals up to 3 months of age:

• Initial dose: 7.5 gm per 50 kg body weight.
• Continuation: 2.5 gm per 50 kg body weight every eight hours interval.

Older animals:

• Initial dose: 10 gm per 50 kg body weight.
• Continuation: 5 gm per 50 kg body weight every twelve hours interval.
• Total period of treatment should not normally exceed 7 days. Or as directed by the registered Veterinary physician.

For external use: Use externally as per requirement or prescribed by a registered veterinary doctor.

With medicine: Topical Sulfanilamide has no effect with oral or parenteral drugs.
With food & others: No interaction was found with feed.

In therapeutic doses Sulphanilamide Powder is relatively non-toxic, but prolonged treatment has been known to cause agranulocytosis, haemolytic anaemia and avitaminosis-K. Where prolonged treatment is undertaken, patients should be watched with care. Sulphanilamide Powder occasionally causes crystalluria, particularly when urinary pH is low. Always ensure adequate water intake during treatment and take particular care in the case of animals suffering from renal damage.

Includes allergic rashes, diarrhoea, dehydration, debility, loss of appetite, hypogalactia, digestive disturbances in ruminants and in other species depression, nausea, vomiting, crystalluria, haemolytic anaemia.

In recommended dosage it is safe in pregnancy & lactation.

Avoid oral administration. The total period of treatment should not exceed seven days. To be kept in a well closed container.

An overdose of topical Sulfanilamide is not expected to be dangerous.

Protect from light, store in a cool and dry place. Keep out of reach of children.