Ivermectin (Oral Solution)

Veterinary

Indications

Poultry: Ivermectin (A-Mectin Vet) is indicated for infestations caused by external parasites such as mites, lice, ticks, fleas etc. and round worm such as Ascaridia galli, Heterakis gallinarum, Cooperia spp. etc.

Cattle, Sheep/Goat: For the treatment of external parasites such as ticks, mites, lice, fleas etc. and some round worms.

Pharmacology

Ivermectin is a member of the macrocyclic lactone class of endectocides which have a unique mode of action. Compounds of the class bind selectively and with high affinity to glutamate-gated chloride ion channels which occur in invertebrate nerve and muscle cells. This leads to an increase in the permeability of the cell membrane to chloride ions with hyperpolarization of the nerve or muscle cell, resulting in paralysis and death of the parasite. Compounds of this class may also interact with other ligand-gated chloride channels, such as those gated by the neurotransmitter gamma-aminobutyric acid (GABA). The margin of safety for compounds of this class is attributable to the fact that mammals do not have glutamate-gated chloride channels, the macrocyclic lactones have a low affinity for other mammalian ligand-gated chloride channels and they do not readily cross the blood-brain barrier.

Dosage & Administration

For oral administration only.

Poultry
: 0.02-0.04 ml/kg body weight (0.2–0.4 mg/kg). Dose may be repeated after 10-14 days.

Pigeon
: 1 ml/L drinking water.

Cattle, Sheep/Goat
: 1 ml/50 kg body weight. Dose may be repeated after 14-28 days. Or, as directed by the Registered Veterinary Physician.
* চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন

Interaction

With medicine: Bioavailability may be increased with Levamisole.
With food & others: Not known.

Contraindications

Contraindicated in animals or birds hypersensitive to Ivermectin.

Side Effects

  • Common side effects: Ivermectin (A-Mectin Vet) is well tolerated in recommended dose.
  • Rare side effects: In some cases diarrhea, ataxia, blindness, abdominal swelling may occur.

Pregnancy & Lactation

May be administered to pregnant animals. But risk & necessity should be considered during administration of medicine in pregnant animals.

Precautions & Warnings

Wash hands carefully after using this product.

Withdrawal Period-
  • Poultry: Meat should not be consumed up to 8 days after using this drug, Eggs should not be consumed up to 7 days after using this drug.
  • Cattle: Meat should not be consumed up to 14 days after using this drug, Milk should not be used in cows producing milk for human consumption.

Overdose Effects

Ivermectin has safety index of 30 times the recommended dose in cattle.

Storage Conditions

Store below 30°C and dry place, protected from light. Keep all medicines out of reach of children.