Furosemide

Veterinary

Indications

Furosemide increase urine volume by reducing the efficiency of sodium resorbing processes and so increase water loss from the body. Indicated for the treatment of ascites, udder edema, pulmonary congestion, renal failure, acute non-inflammatory tissue edema etc. It also helps to excrete poisons or drug overdose by increasing urine flow.

Description

Furosemide is a diuretic that increases urine flow when there is fluid retention & edema or ascites due to heart failure, liver disease, hypoproteinaemia, inflammation or trauma. It induces urine flow in renal failure & reduces blood pressure. It also helps to excrete poisons or drug overdose by increasing urine flow.

Pharmacology

Furosemide is a monosulphonyl diuretic. It is an effective diuretic that retains its activity even in low glomerular filtration rate (GFR). Furosemide has a distinctive action on renal tubular function. It affects a peak diuresis far greater than that observed with other agents. Other features are (I) prompt onset of action (II) inhibition of sodium and chloride transport in the ascending limb of the loop of Henle and (III) independence of their action from acid-base balance changes. Furosemide acts primarily to inhibit electrolyte reabsorption in the thick ascending limb of the loop of Henle.

Dosage & Administration

For oral administration only.
  • Cattle: 1 bolus/ animal once daily.
  • Dog: 2-4 mg/kg body weight once to three times daily.
  • Cat: 1-2 mg/kg body weight once or twice daily.
  • Poultry: 0.5-1 mg/kg body weight.
The bolus may be administered orally directly or through mixing with required amount of feed/water by grinding the bolus. Or as directed by the Veterinary Physicians.
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Contraindications

Contraindicated to animal hypersensitive to Furosemide.

Side Effects

Alkalosis, uric acid retention and may rarely produce acute gout, hyperglycemia & glycosuria.

Precautions & Warnings

Withdrawal Periodঃ Meat & Milk: 2 days, Egg: Not known

Storage Conditions

Store in a cool and dry place, protected from light. Keep all medicines out of reach of children.

Available Brand Names