Ceftiofur Sodium
Veterinary
Indications
Livestock: Ceftiofur Vet is indicated for the treatment of bovine respiratory diseases (shipping fever, pneumonia) associated with Mannheimia haemolytica, Pasteurella multocida & Histophilus somni, acute bovine interdigital necrobacillosis (foot rot, pododermatitis) associated with Fusobacterium necrophorum & Bacteroides melaninogenicus and genital tract infections (endometritis, postpuerperial metritis, toxic puerperal metritis, pyometra) associated with E. coli, Fusobacterium necrophorum, Arcanobacterium pyogenes.
Poultry: Ceftiofur Vet is indicated for the control of early chick mortality associated with E. coli in day-old chicks and day-old turkey poults.
Poultry: Ceftiofur Vet is indicated for the control of early chick mortality associated with E. coli in day-old chicks and day-old turkey poults.
Pharmacology
Ceftiofur is a broad spectrum third generation Cephalosporin and beta-lactam antibiotic that is resistant to the action of beta-lactamase. It is active against both gram-positive and gram-negative bacteria. The additional benefit of Ceftiofur is that its metabolite, desfuroylceftiofur has also antimicrobial activity. It kills bacteria by inhibiting the synthesis of bacterial cell wall.
Dosage & Administration
Route of administration: For intramuscular/ subcutaneous injection only.
Cattle/Sheep/Goat: 1.1-2.2 mg/kg body weight (1 ml/23-45 kg) by IM injection once daily for 3-5 days.
Dog: 2.2 mg/kg body weight (1 ml/23 kg) by SC injection once daily for 5-14 days.
Horse: 2.2-4.4 mg/kg body weight (1 ml/12-23 kg) by IM injection once daily & continued for 2 days after disappearing of clinical signs.
Swine: 3-5 mg/kg body weight by IM injection once daily for 3 consecutive days.
Day-Old Chicks: 0.08-0.2 mg/chick by SC injection. 1 ml (50 mg/ml) reconstituted solution will be required for the treatment of approximately 250 to 625 day-old chicks.
Day-Old Turkey Poults: 0.17-0.5 mg/poult by SC injection in the neck region. 1 ml (50 mg/ml) reconstituted solution will be required for the treatment of approximately 100 to 294 day-old turkey poults. Or as directed by the registered Veterinary Physician.
Cattle/Sheep/Goat: 1.1-2.2 mg/kg body weight (1 ml/23-45 kg) by IM injection once daily for 3-5 days.
Dog: 2.2 mg/kg body weight (1 ml/23 kg) by SC injection once daily for 5-14 days.
Horse: 2.2-4.4 mg/kg body weight (1 ml/12-23 kg) by IM injection once daily & continued for 2 days after disappearing of clinical signs.
Swine: 3-5 mg/kg body weight by IM injection once daily for 3 consecutive days.
Day-Old Chicks: 0.08-0.2 mg/chick by SC injection. 1 ml (50 mg/ml) reconstituted solution will be required for the treatment of approximately 250 to 625 day-old chicks.
Day-Old Turkey Poults: 0.17-0.5 mg/poult by SC injection in the neck region. 1 ml (50 mg/ml) reconstituted solution will be required for the treatment of approximately 100 to 294 day-old turkey poults. Or as directed by the registered Veterinary Physician.
* চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Interaction
With medicine: Not known. With feed & others: Not known.
Contraindications
Contraindicated to the animals hypersensitive to Ceftiofur Sodium.
Side Effects
Common side effects: The use of Ceftiofur results in some signs of immediate and transient local pain at the site of injection of the animal. Rare side effects: Eosinophilia, full-blown anaphylaxis, rashes may be seen.
Pregnancy & Lactation
The effects of Ceftiofur Sodium on the reproductive performance, pregnancy & lactation have not been determined yet.
Precautions & Warnings
To avoid possible allergic reactions, users are advised to avoid direct contact of Ceftiofur sodium with the skin or mucous membranes.
Withdrawal time: Meat & Milk-0 (Zero) day.
Withdrawal time: Meat & Milk-0 (Zero) day.
Overdose Effects
No evidence of systemic toxicity was observed following administration of an overdose in cattle.
Reconstitution
0.25 g: Shake the vial containing Ceftiofur Sodium sterile powder & then add 5 ml water for injection (WFI) gradually. Shake well until the powder dissolved properly.
0.5 g: Shake the vial containing Ceftiofur Sodium sterile powder & then add 10 ml water for injection (WFI) gradually. Shake well until the powder dissolved properly.
1 g: Shake the vial containing Ceftiofur Sodium sterile powder & then add 20 ml water for injection (WFI) gradually. Shake well until the powder dissolved properly.
0.5 g: Shake the vial containing Ceftiofur Sodium sterile powder & then add 10 ml water for injection (WFI) gradually. Shake well until the powder dissolved properly.
1 g: Shake the vial containing Ceftiofur Sodium sterile powder & then add 20 ml water for injection (WFI) gradually. Shake well until the powder dissolved properly.
Storage Conditions
Store below 30°C temperature, protected from light. The reconstituted injection may be stored in a refrigerator 2°-8°C for up to seven (7) days or at controlled room temperature 20°-25°C for up to twelve (12) hours. Keep all medicines out of reach of children.
