Cetalkonium Chloride + Choline Salicylate

Indications

This is indicated for the fast relief of pain, discomfort and inflammation caused by Mouth ulcer/Aphthous ulcer/Canker sore, Cold sore/Fever blister, Denture sore, Irritation from braces, Gum swelling, and sore spots due to orthodontic device.

Pharmacology

Choline salicylate has an analgesic & anti-inflammatory effect. Like salicylic acid Choline salicylate has no antithrombotic activity. The pharmacological actions of choline salicylate are thought to be primarily mediated through inhibition of prostaglandin production. Cetalkonium chloride is an antiseptic, being bactericidal towards both Gram-positive and Gram-negative organisms.

Absorption: Choline salicylate is absorbed from the gut
Distribution: Throughout extracellular water and most tissues
Plasma Half-life: 2-4 hours
Excretion: Mainly in the Urine
Protein binding: 80-90%

Dosage & Administration

Adult: Wash hands, apply ½ inch of gel on to the sore area. This can be repeated after every 3 hours.
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Interaction

Salicylates may enhance the effect of anticoagulants and inhibit the action of uricosurics.

Contraindications

Not to be used in:
  • If allergic to salicylates, e.g. Aspirin
  • If have an active peptic ulcer

Side Effects

Salicylates may produce bronchospasm and induce asthma attacks in susceptible patients.

Pregnancy & Lactation

There is clinical evidence of the safety of salicylates in pregnancy. This medicine may pass into breast milk in very small amounts but is unlikely to have any adverse effects on a nursing infant.

Precautions & Warnings

Do not exceed the recommended dose.

Therapeutic Class

Non-steroidal Anti-inflammatory Drugs (NSAIDs), Preparations for Oral Ulceration & Inflammation

Storage Conditions

Store in a cool and dry place, away from light. Keep out of the reach of children.

Available Brand Names