Metronidazole + Neomycin Sulphate + Polymyxin B + Nystatin

Indications

This combination is indicated in-
  • Vaginal trichomoniasis
  • Vaginal leucorrhoeas
  • Mixed vaginal infections (Fungal or Bacterial).

Composition

Each vaginal suppository contains-
  • Metronidazole BP 200 mg
  • Neomycin Sulphate BP 35000 IU
  • Polymyxin B Sulphate BP 35000 IU
  • Nystatin BP 100000 IU.

Pharmacology

Metronidazole, a nitroimidazole, is active against various anerobic bacteria and protozoa. Nystatin is a polyene antibiotic with antifungal activity. Neomycin is an aminoglycoside. It is bactericidal and active against some gram-positive and gram-negative organisms. Polymyxin is active against gram-negative organisms including Pseudomonas aeruginosa.

Dosage & Administration

One suppository in the vagina at bedtime for 12 days or as directed by the physician.
* চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন

Contraindications

Contraindicated to the patients who are hypersensitive to Metronidazole, Neomycin Sulphate, Polymyxin B Sulphate and Nystatin.

Side Effects

Skin rash, urticaria may occur rarely.

Pregnancy & Lactation

Caution should be practiced in pregnancy and lactation.

Precautions & Warnings

Caution should be taken in case of renal impairment.

Therapeutic Class

Drugs used in Vaginal and Vulval condition

Storage Conditions

Store in a cool and dry place, away from light & children.