Metronidazole + Neomycin Sulphate + Polymyxin B + Nystatin
Indications
This combination is indicated in-
- Vaginal trichomoniasis
- Vaginal leucorrhoeas
- Mixed vaginal infections (Fungal or Bacterial).
Composition
Each vaginal suppository contains-
- Metronidazole BP 200 mg
- Neomycin Sulphate BP 35000 IU
- Polymyxin B Sulphate BP 35000 IU
- Nystatin BP 100000 IU.
Pharmacology
Metronidazole, a nitroimidazole, is active against various anerobic bacteria and protozoa. Nystatin is a polyene antibiotic with antifungal activity. Neomycin is an aminoglycoside. It is bactericidal and active against some gram-positive and gram-negative organisms. Polymyxin is active against gram-negative organisms including Pseudomonas aeruginosa.
Dosage & Administration
One suppository in the vagina at bedtime for 12 days or as directed by the physician.
* চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Contraindications
Contraindicated to the patients who are hypersensitive to Metronidazole, Neomycin Sulphate, Polymyxin B Sulphate and Nystatin.
Side Effects
Skin rash, urticaria may occur rarely.
Pregnancy & Lactation
Caution should be practiced in pregnancy and lactation.
Precautions & Warnings
Caution should be taken in case of renal impairment.
Therapeutic Class
Drugs used in Vaginal and Vulval condition
Storage Conditions
Store in a cool and dry place, away from light & children.