Indications
This is indicated for the fast relief of pain, discomfort and inflammation caused by Mouth ulcer/Aphthous ulcer/Canker sore, Cold sore/Fever blister, Denture sore, Irritation from braces, Gum swelling, and sore spots due to orthodontic device.
Pharmacology
Choline salicylate has an analgesic & anti-inflammatory effect. Like salicylic acid Choline salicylate has no antithrombotic activity. The pharmacological actions of choline salicylate are thought to be primarily mediated through inhibition of prostaglandin production. Cetalkonium chloride is an antiseptic, being bactericidal towards both Gram-positive and Gram-negative organisms.
Absorption: Choline salicylate is absorbed from the gut
Distribution: Throughout extracellular water and most tissues
Plasma Half-life: 2-4 hours
Excretion: Mainly in the Urine
Protein binding: 80-90%
Absorption: Choline salicylate is absorbed from the gut
Distribution: Throughout extracellular water and most tissues
Plasma Half-life: 2-4 hours
Excretion: Mainly in the Urine
Protein binding: 80-90%
Dosage & Administration
Adult: Wash hands, apply ½ inch of gel on to the sore area. This can be repeated after every 3 hours.
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Interaction
Salicylates may enhance the effect of anticoagulants and inhibit the action of uricosurics.
Contraindications
Not to be used in:
- If allergic to salicylates, e.g. Aspirin
- If have an active peptic ulcer
Side Effects
Salicylates may produce bronchospasm and induce asthma attacks in susceptible patients.
Pregnancy & Lactation
There is clinical evidence of the safety of salicylates in pregnancy. This medicine may pass into breast milk in very small amounts but is unlikely to have any adverse effects on a nursing infant.
Precautions & Warnings
Do not exceed the recommended dose.
Therapeutic Class
Non-steroidal Anti-inflammatory Drugs (NSAIDs), Preparations for Oral Ulceration & Inflammation
Storage Conditions
Store in a cool and dry place, away from light. Keep out of the reach of children.