Otetra-Vet Bolus Tablet

Oxytetracycline is under group of Tetracycline’s which bind to the 30s ribosomal subunit of bacterial ribosome and interfere with the binding of aminoacyl-tRNA to the mRNA molecule in ribosome complex. Thereby interfere with bacterial protein synthesis in growing or multiplying bacteria leading to bacteriostatic but higher concentration results bacteriocidal action.

Oxytetracycline bolus tablet:
Cattle and Buffalo 50-100 kg-

• Preventive: ½ caplet
• Curative: 1 caplet
• Disease of the respiratory tract and others: 2-4 caplets

Sheep and Goat 10-20 kg

• Preventive: ½-2/3 caplet
• Curative: 1 caplet
• Disease of the respiratory tract and others: 1 caplet

Horse Up to 150 kg

• Preventive: 1 caplet
• Curative: 1-1½ caplet
• Disease of the respiratory tract and others: 2 caplets

Horse Above 150 kg 

• Preventive: 1½-2 caplets
• Curative: 2-3 caplet
• Disease of the respiratory tract and others: 3-4 caplets

Dog and Cat

• Disease of the respiratory tract and others:½ caplet

Oxytetracycline powder:
Treatment: Oxytetracycline powder as 100 mg/kg body weight or 1 gm per 2.5 litre drinking water for 3-5 consecutive days or 50 gm per 100 kg feed for 7 consecutive days.

Prevention/Growth Promotion: Oxytetracycline powder as 50 mg/kg body weight or 1 gm per 5 litre drinking water for 3-5 consecutive days or 35 gm per 100 kg feed for 7-10 consecutive days.

Calves:

• Treatment: 40 mg Oxytetracycline per kg body weight for 3-5 consecutive days.
• Prevention/ Growth Promotion: 20 mg Oxytetracycline powder per kg body weight for 7-10 consecutive days.

Fishes: 11 gm-16 gm Oxytetracycline powder per 100 kg fishes.
Honey Bees: 0.5 gm Oxytetracycline powder per colony. Usually 3 dustings are required at 4-5 days interval.

Long-Acting Injectable Solution:

• Cattle, Buffaloes, Sheep, Goat & Deer: Single dose treatment of 1 ml per 10 kg body weight. (or, 20 mg per kg body weight) by IM route.
• Poultry & Rabbit: Single dose treatment of 0.25 ml per kg body weight (or, 50 mg per kg body weight) by subcutaneous route. Severe infections may require re-treatment at 3 to 5 days following initial injection. Or, as advised by the veterinary physician

With medicine: Efficacy of penicillin, iron dextran can be decreased when used with Otetra-Vet. The serum concentration of Otetra-Vet can be decreased when used with Bismuth subsalicylate, Calcium gluconate/lactate, aluminium, magnesium & zinc salts. Allow 2-3 hours between doses of Otetra-Vet and antacids.

With feed & others: Not known.

Oxytetracycline Powder is contraindicated to use with calcium containing drug or food.

General toxicity is low although collapse has been reported with tetracycline in weak and debilitated animals.

Oxytetracycline Powder should not be used during pregnancy because of the risk of hepatotoxicity in the mother as well as the effects on the developing fetus. Use in pregnancy and lactation may result in impaired bone growth and reduce milk production.

Milk from lactating cows should not be taken for human consumption during treatment for 48 hours thereafter. Otetra-Vet powder should not be administered to fish for more than 12 consecutive days without at least a
few days break.

Otetra-Vet has a wide safety margin and overdosing is unlikely to produce toxic symptoms.

Store below 30° C temperature. Protect from light. Keep out of reach of children.