Indications

Ezylife Max is indicated in the following conditions-
  • Constipation of any etiology
  • Relief from prolonged & recurrent constipation
  • Bowel clearance before surgery, childbirth or radiological investigations.

Pharmacology

Sodium Picosulfate is a triarylmethane group derivative stimulant laxative. After oral administration it is activated by the colonic bacteria and acts locally in the colon. The active form then stimulates the nerve endings of the intestinal wall and results in colonic peristalsis with promotion of accumulation of water and electrolytes in the colonic lumen. This results in stimulation of defecation, reduction of transit time and softening of the stool. Stimulation of the rectum causes increased motility and a feeling of rectal fullness. The rectal effect may help to restore the "call to stool".

Dosage & Administration

For oral administration. The following dosages are recommended to be taken at night to produce evacuation the following morning. It is recommended to start with the lowest dose. The dose may be adjusted up to the maximum recommended dose to produce regular stools. The maximum recommended daily dose should not be exceeded:

10 mg tablet dose:
  • Adults and children over 10 years of age: 5-10 mg per day.
  • Children aged 4-10 years: 2.5-5 mg per day.
Oral Solution (5 mg/5 ml) dose:
  • Adults and children over 10 years of age: 5-10 ml or one to two teaspoonful per day.
  • Children aged 4-10 years: 2.5-5 ml or half to one teaspoonful per day.
  • Children from One month to 4 years of age: 0.25 ml/kg body weight per day.
Concentrated Oral Solution (7.5 mg/ml) dose:
  • Adults and children over 10 years of age: 0.67-1.33 ml per day.
  • Children aged 4-10 years: 0.33-0.67 ml per day.
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Interaction

The concomitant use of diuretics or adreno-corticosteroids may increase the risk of electrolyte imbalance if excessive doses are taken. Concurrent administration of antibiotics may reduce the laxative action of Ezylife Max.

Contraindications

Ileus or intestinal obstruction, severe painful and/or feverish acute abdominal conditions (e.g. appendicitis) potentially associated with nausea and vomiting, acute inflammatory bowel diseases, severe dehydration, known hypersensitivity to Sodium Picosulfate or any other component of the product.

Side Effects

Hypersensitivity, dizziness, syncope, vasovagal response, gastrointestinal disorders, diarrhea, abdominal pain and abdominal cramps, nausea, vomiting.

Pregnancy & Lactation

There are no reports of undesirable or damaging effects during pregnancy or to the foetus attributable to the use of this product. Use of the drug should be avoided during the first trimester. Clinical data show that neither the active moiety of sodium Picosulfate (BHPM or bis-(p hydroxyphenyl)-pyridyl-2-methane) nor its glucuronides are excreted into the milk of healthy lactating females.

Precautions & Warnings

Prolonged excessive use may lead to fluid and electrolyte imbalance and hypokalemia. Harmful for those suffering from alcoholism. To be taken into account in pregnant or breast-feeding women, children and high-risk groups such as patients with liver disease or epilepsy.

Overdose Effects

Laxatives when taken in chronic overdosage may cause chronic diarrhea, abdominal pain, hypokalemia, secondary hyperaldosteronism, and renal calculi. Renal tubular damage, metabolic alkalosis, and muscle weakness secondary to hypokalemia have also been described in association with chronic laxative abuse.

Therapeutic Class

Stimulant Laxative

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

Chemical Structure

Molecular Formula : C18H15NNa2O9S2
Chemical Structure : Chemical Structure of Sodium Picosulfate

Common Questions about Ezylife Max 7.5 mg/ml Oral Solution

What is Ezylife Max 7.5 mg/ml Solution?

Ezylife Max 7.5 mg/ml Solution belongs to the class of laxatives.

What are the uses of the Ezylife Max 7.5 mg/ml Solution?

Ezylife Max 7.5 mg/ml Solution is used in the treatment of constipation.

How long do I need to use Ezylife Max 7.5 mg/ml Solution before I see improvement in my condition?

Ezylife Max 7.5 mg/ml Solution is to be taken till the time you see an improvement in your health conditions.

At what frequency do I need to use Ezylife Max 7.5 mg/ml Solution?

Ezylife Max 7.5 mg/ml Solution should be taken in the dosage as prescribed by the doctor.

Should I use Ezylife Max 7.5 mg/ml Solution empty stomach, before food or after food?

Ezylife Max 7.5 mg/ml Solution should be taken at bed-time as it requires 6-8 hours to show effect.

What are the instructions for the storage and disposal of Ezylife Max 7.5 mg/ml Solution?

Ezylife Max 7.5 mg/ml Solution should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

Is Ezylife Max 7.5 mg/ml Solution safe for pregnant women?

Ezylife Max 7.5 mg/ml Solution is not prescribed to pregnant women unless necessary. Consult your doctor beforehand.

Is Ezylife Max 7.5 mg/ml Solution safe for breastfeeding women?

Breastfeeding women are not suggested to take Ezylife Max 7.5 mg/ml Solution unless necessary. Consult your doctor beforehand.

Is Ezylife Max 7.5 mg/ml Solution a habit forming drug?

No case of addiction has been reported yet.

What if I miss a dose of Ezylife Max 7.5 mg/ml Solution?

Take Ezylife Max 7.5 mg/ml Solution as soon as you remember. However, stick to your routine if it's the time for the next dose. Do not double the dose.

Quick Tips

  • Together with Ezylife Max 7.5 mg/ml Solution, taking a fiber-rich diet containing whole grain bread and cereals, bran, fruits and green leafy vegetables, is essential to maintain healthy bowel function.
  • Avoid taking a Ezylife Max 7.5 mg/ml Solution for more than 1 week, unless prescribed by the doctor, as it leads to dependency on the laxative action to produce a bowel movement.
  • Take Ezylife Max 7.5 mg/ml Solution after 2 hours from other medicines, as it may interfere with the absorption of other medicines.
  • Ezylife Max 7.5 mg/ml Solution should be preferably taken at bedtime because it requires 6 to 8 hours to show impact.
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Pack Image of Ezylife Max 7.5 mg Oral Solution Pack Image: Ezylife Max 7.5 mg Oral Solution